The front line of research into immunoglobin G4-related disease - Do autoantibodies cause immunoglobin G4-related disease?
نویسندگان
چکیده
منابع مشابه
Esophageal Involvement of Immunoglobulin G4-Related Disease
Immunoglobulin G4 (IgG4)-related disease is characterized by the typical histopathological features of a dense lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells, a high ratio of IgG4- to IgG-positive cells, storiform fibrosis (cellular fibrosis organized in an irregular whorled pattern), obliterative phlebitis, and variable presence of eosinophils. The disease exhibits systemic in...
متن کاملNasal manifestations of immunoglobulin G4-related disease.
OBJECTIVES/HYPOTHESIS Immunoglobulin (Ig)G4-related disease is a systemic syndrome, characterized by sclerosing lesions that mainly affect the exocrine tissue. Although some patients with IgG4-related disease complain of nasal symptoms, there are few reports concerning the nasal manifestations of this disease. We investigated the clinical and pathological features of the nasal manifestations of...
متن کاملImmunoglobulin G4‐related disease: a rare steroid‐responsive disease
A 70-year-old man presented with progressive dyspnoea and weight loss. Physical examination revealed only mild pale conjunctiva. The workup showed mild anaemia, mild impaired renal function, and high globulin level. Multiple myeloma was excluded by normal serum protein electrophoresis. The chest radiography and computed tomography (CT) revealed bilateral multifocal patchy infiltration with medi...
متن کاملImmunoglobulin G4-related sclerosing disease of the paranasal sinus.
BACKGROUND Immunoglobulin G4 (IgG4)-related sclerosing disease is a systemic disease characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs. We present a case of a 69-year-old man with maxillary sinus IgG4 sclerosing disease, with orbital invasion treated with rituximab and dexamethasone pulse therapy. Surgery was used as well to debulk the disease...
متن کاملImmunoglobulin G4-associated cholangitis: one variant of immunoglobulin G4-related systemic disease.
IgG4-associated cholangitis (IAC) is a recently defined disease entity which shares a number of clinical, biochemical, and radiological features with primary sclerosing cholangitis (PSC). In contrast to PSC, IAC responds to immunosuppressive treatment, is not associated with inflammatory bowel disease, and mainly affects elderly men above the age of 60 years. Today, IAC is regarded as one varia...
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ژورنال
عنوان ژورنال: Modern Rheumatology
سال: 2019
ISSN: 1439-7595,1439-7609
DOI: 10.1080/14397595.2018.1558519